Perrywalton
Tamoxifen is a selective estrogen receptor modulator (SERM) widely used in the management of breast cancer, particularly for hormone receptor-positive cases. Its primary Uses of Tamoxifen for breast cancer include both treatment and prevention. In treatment, tamoxifen is prescribed for women and men diagnosed with early, locally advanced, or metastatic breast cancer. It is particularly effective in patients with estrogen receptor-positive tumors, as it blocks estrogen from binding to cancer cells, thereby inhibiting their growth. Tamoxifen is often administered after surgery and radiation as adjuvant therapy to reduce the risk of cancer recurrence. Studies indicate that it can lower the risk of breast cancer recurrence by approximately 17% and reduce mortality from breast cancer by about 9%. In terms of prevention, tamoxifen is recommended for women aged 35 and older who are at high risk of developing breast cancer, including those with a family history or genetic predispositions. It has been shown to decrease the risk of invasive breast cancer by about 40% in these populations. Tamoxifen is typically taken as a daily pill for five years, although benefits may persist long after discontinuation. While effective, patients need to discuss potential side effects, such as an increased risk of uterine cancer and blood clots, with their healthcare providers to weigh the benefits against the risks.
